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1

Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

Homnick, Carl F., Kuo, Michelle S., Bell, Ian M., Erb, Jill M., Freidinger, Roger M., Gallicchio, Steven N., Guare, James P., Guidotti, Maribeth T., Halpin, Rita A., Hobbs, Doug W.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 300 KB

english, 1998

2

Effect of Substituents on Optical Properties and Charge-Carrier Polarity of Squaraine Dyes

Della Pelle, Andrea M., Homnick, Paul J., Bae, Youngju, Lahti, Paul M., Thayumanavan, S.

Journal:

The Journal of Physical Chemistry C

Year:

2014

Language:

english

File:

PDF, 1.78 MB

english, 2014

3

ChemInform Abstract: Complestatin to Chloropeptin I via a Quantitative Acid Catalyzed Rearrangement. Absolute Stereochemical Determination of Complestatin.

H. JAYASURIYA, G. M. SALITURO, S. K. SMITH, J. V. HECK, S. J. GOULD, S. B. SINGH, C. F. HOMNICK, M. K. HOLLOWAY, S. M. PITZENBERGER, M. A. PATANE

Journal:

Year:

1998

File:

PDF, 34 KB

1998

4

ChemInform Abstract: Selective and Controlled Hydrolysis of Chloropeptin I. HIV-1 Integrase Activity of Fragments.

S. B. SINGH, H. JAYASURIYA, D. L. HAZUDA, P. FELOCK, C. F. HOMNICK, M. SARDANA, M. A. PATANE

Journal:

Year:

1999

File:

PDF, 24 KB

1999

5

Asymmetric Synthesis of α,α-Difluoro-β-amino Acid Derivatives from Enantiomerically Pure N-tert-Butylsulfinimines.

Donnette D. Staas, Kelly L. Savage, Carl F. Homnick, Nancy N. Tsou, Richard G. Ball

Journal:

Year:

2003

File:

PDF, 249 KB

2003

6

A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells

Mark W. Embrey, John S. Wai, Timothy W. Funk, Carl F. Homnick, Debbie S. Perlow, Steven D. Young, Joseph P. Vacca, Daria J. Hazuda, Peter J. Felock, Kara A. Stillmock, Marc V. Witmer, Gregory Moyer, W

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 145 KB

english, 2005

7

Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors

H. Marie Langford, Peter D. Williams, Carl F. Homnick, Joseph P. Vacca, Peter J. Felock, Kara A. Stillmock, Marc V. Witmer, Daria J. Hazuda, Lori J. Gabryelski, William A. Schleif

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 140 KB

english, 2008

8

10-Hydroxy-7,8-dihydropyrazino[1′,2′:1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-diones: Potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against integrase mutants

Catherine M. Wiscount, Peter D. Williams, Lekhanh O. Tran, Mark W. Embrey, Thorsten E. Fisher, Vanessa Sherman, Carl F. Homnick, D. Donnette Staas, Terry A. Lyle, John S. Wai, Joseph P. Vacca, ZiQiang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 164 KB

english, 2008

9

Synthesis and evaluation of novel tricyclic benzo[4.5]cyclohepta[1.2]pyridine derivatives as NMDA/NR2B antagonists

Charles J. McIntyre, John A. McCauley, Bohumil Bednar, Rodney A. Bednar, John W. Butcher, David A. Claremon, Michael E. Cunningham, Roger M. Freidinger, Stanley L. Gaul, Carl F. Homnick, Ken S. Koblan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

10

OSL Dosimeters can be used for Remote Dosimetry

Homnick, J., Ibbott, G., Springer, A., Aguirre, F.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

11

A new amine resolution method and its application to 3-aminobenzodiazepines

Kenneth E Rittle, Ben E Evans, Mark G Bock, Robert M DiPardo, Willie L Whitter, Carl F Homnick, Daniel F Veber, Roger M Freidinger

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 138 KB

english, 1987

12

Complestatin to chloropeptin I via a quantitative acid catalyzed rearrangement. Absolute stereochemical determination of complestatin.

Hiranthi Jayasuriya, Gino M. Salituro, Scott K. Smith, James V. Heck, Steven J. Gould, Sheo B. Singh, Carl F. Homnick, M.Katharine Holloway, Steven M. Pitzenberger, Michael A. Patane

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 207 KB

english, 1998

13

Selective and controlled hydrolysis of chloropeptin I. HIV-1 integrase activity of fragments

Sheo B. Singh, Hiranthi Jayasuriya, Daria L. Hazuda, Peter Felock, Carl F. Homnick, Mohinder Sardana, Michael A. Patane

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 162 KB

english, 1998

14

Bicyclic pyridones as potent, efficacious and orally bioavailable thrombin inhibitors

Craig A Coburn, Diane M Rush, Peter D Williams, Carl Homnick, Elizabeth A Lyle, S.Dale Lewis, Bobby J Lucas Jr., Jillian M Di Muzio-Mower, Marylou Juliano, Julie A Krueger, Kari Vastag, I-Wu Chen, Jos

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 125 KB

english, 2000

15

Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase

Douglas C Beshore, Ian M Bell, Christopher J Dinsmore, Carl F Homnick, J.Christopher Culberson, Ronald G Robinson, Christine Fernandes, Eileen S Walsh, Marc T Abrams, Hema G Bhimnathwala, Joseph P Dav

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 293 KB

english, 2001

16

Selective α1a adrenergic receptor antagonists based on 4-aryl-3,4-dihydropyridine-2-ones

Philippe G Nantermet, James C Barrow, Harold G Selnick, Carl F Homnick, Roger M Freidinger, Raymond S.L Chang, Stacey S O'Malley, Duane R Reiss, Theodore P Broten, Richard W Ransom, Douglas J Pettibon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 144 KB

english, 2000

17

Comparison of effects of an intrapulmonary percussive ventilator to standard aerosol and chest physiotherapy in treatment of cystic fibrosis

Dr. Douglas N. Homnick, Fred White, Carol de Castro

Journal:

Pediatric Pulmonology

Year:

1995

Language:

english

File:

PDF, 515 KB

english, 1995

18

Cyproheptadine is an effective appetite stimulant in cystic fibrosis

Douglas N. Homnick, Benjamin D. Homnick, Andrew J. Reeves, John H. Marks, Ronald S. Pimentel, Sally K. Bonnema

Journal:

Pediatric Pulmonology

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

19

Long-term trial of cyproheptadine as an appetite stimulant in cystic fibrosis

Douglas N. Homnick, John H. Marks, Karyl L. Hare, Sally K. Bonnema

Journal:

Pediatric Pulmonology

Year:

2005

Language:

english

File:

PDF, 104 KB

english, 2005

20

Predictors of insufficient sweat production during confirmatory testing for cystic fibrosis

Mary Kleyn, Steven Korzeniewski, Violanda Grigorescu, William Young, Douglas Homnick, Amy Goldstein-Filbrun, John Schuen, Samya Nasr

Journal:

Pediatric Pulmonology

Year:

2011

Language:

english

File:

PDF, 87 KB

english, 2011

21

A continuous-flow electrophile scavenger prepared by a simple grafting procedure

Jennifer A. Tripp, Trevor P. Needham, Erin M. Ripp, Brian G. Konzman, Paul J. Homnick

Journal:

Reactive and Functional Polymers

Year:

2010

Language:

english

File:

PDF, 307 KB

english, 2010

22

IN-PLANT, CONTINUOUS HOT-GAS BLANCHING OF SPINACH

JACK W. RALLS, HARRY J. MAAGDENBERG, NABIL L. YACOUB, DOUGLAS HOMNICK, MARK ZINNECKER, WALTER A. MERCER

Journal:

Journal of Food Science

Year:

1973

Language:

english

File:

PDF, 376 KB

english, 1973

23

A potent cyclic hexapeptide analogue of somatostatin

Veber, Daniel F., Freidinger, Roger M., Perlow, Debra Schwenk, Paleveda, William J., Holly, Frederick W., Strachan, Robert G., Nutt, Ruth F., Arison, Byron H., Homnick, Carl, Randall, William C.

Journal:

Year:

1981

File:

PDF, 436 KB

1981

24

Synthesis of thyrotropin-releasing hormone analogs with selective central nervous system effects

Nutt, Ruth F., Holly, Frederick W., Homnick, Carl, Hirschmann, Ralph, Veber, Daniel F., Arison, Byron H.

Journal:

Journal of Medicinal Chemistry

Year:

1981

Language:

english

File:

PDF, 1.02 MB

english, 1981

25

Phosphatidylcholine-specific conjugated dienes by high-pressure liquid chromatography (HPLC) are elevated in cystic fibrosis plasma

T. Ringer, D. Homnick, M. DeLoof, J. Cox, S. Cox, J. Zimmerman

Journal:

Free Radical Biology and Medicine

Year:

1993

Language:

english

File:

PDF, 166 KB

english, 1993

26

Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist

Rachel K. Conley, Alan Wheeldon, Janine K. Webb, Robert M. DiPardo, Carl F. Homnick, Mark G. Bock, Tsing-Bau Chen, Raymond S.L. Chang, Douglas J. Pettibone, Susan Boyce

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 388 KB

english, 2005

27

Glucagon releasing activity of a cyclic peptide related to somatostatin

TERRY A. LYLE, ROGER M. FREIDINGER, RUTH F. NUTT, CARL F. HOMNICK, RICHARD SAPERSTEIN, DANIEL F. VEBER

Journal:

Chemical Biology & Drug Design

Year:

1987

Language:

english

File:

PDF, 362 KB

english, 1987

28

Value of repeat cranial computed axial tomography scanning in patients with minimal head injury

Ziad C Sifri, David H Livingston, Robert F Lavery, Adena T Homnick, Anne C Mosenthal, Alicia M Mohr, Carl J Hauser

Journal:

The American Journal of Surgery

Year:

2004

Language:

english

File:

PDF, 62 KB

english, 2004

29

Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences

Youwei Yan, Vinod Sardana, Bei Xu, Carl Homnick, Wasyl Halczenko, Carolyn A. Buser, Michael Schaber, George D. Hartman, Hans E. Huber, Lawrence C. Kuo

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.51 MB

english, 2004

30

Making airway clearance successful

Douglas N. Homnick

Journal:

Paediatric Respiratory Reviews

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

31

Carotenoid levels in normal children and in children with cystic fibrosis

Douglas N. Homnick, Janice H. Cox, Michael J. DeLoof, Thomas V. Ringer

Journal:

The Journal of Pediatrics

Year:

1993

Language:

english

File:

PDF, 418 KB

english, 1993

32

Single- and multiple-dose–response relationships of beta-carotene in cystic fibrosis

Douglas N. Homnick, Carol R. Spillers, Steven R. Cox, Janice H. Cox, Lori A. Yelton, Michael J. DeLoof, Lawerence K. Oliver, Thomas V. Ringer

Journal:

The Journal of Pediatrics

Year:

1995

Language:

english

File:

PDF, 396 KB

english, 1995

33

Letter

Douglas N. Homnick, Thomas V. Ringer

Journal:

The Journal of Pediatrics

Year:

1996

Language:

english

File:

PDF, 115 KB

english, 1996

34

Guest Editorial

Bruce K. Rubin, Douglas N. Homnick

Journal:

Paediatric Respiratory Reviews

Year:

2007

Language:

english

File:

PDF, 107 KB

english, 2007

35

A stereocontrolled synthesis of hydroxyethylene dipeptide isosteres using novel, chiral aminoalkyl epoxides and .gamma.-(aminoalkyl)-.gamma.-lactones

Evans, Ben E., Rittle, Kenneth E., Homnick, Carl F., Springer, James P., Hirshfield, Jordan, Veber, Daniel F.

Journal:

Journal of Organic Chemistry

Year:

1985

Language:

english

File:

PDF, 1.93 MB

english, 1985

36

In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α 1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia

Barrow, James C., Nantermet, Philippe G., Selnick, Harold G., Glass, Kristen L., Rittle, Kenneth E., Gilbert, Kevin F., Steele, Thomas G., Homnick, Carl F., Freidinger, Roger M., Ransom, Rick W., Klin

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 329 KB

english, 2000

37

Design of nonpeptidal ligands for a peptide receptor: cholecystokinin antagonists

Evans, B. E., Rittle, K. E., Bock, M. G., DiPardo, R. M., Freidinger, R. M., Whitter, W. L., Gould, N. P., Lundell, G. F., Homnick, C. F.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 1.33 MB

english, 1987

38

Nonreducible cyclic analogues of somatostatin

Veber, Daniel F., Strachan, Robert G., Bergstrand, Susan J., Holly, Frederick W., Homnick, Carl F., Hirschmann, Ralph, Torchiana, Mary L., Saperstein, Richard

Journal:

Journal of the American Chemical Society

Year:

1976

Language:

english

File:

PDF, 391 KB

english, 1976

39

A Selective Protection of 2,3-Diaminopropionic Acid

Egbertson, M. S., Homnick, C. F., Hartman, G. D.

Journal:

Synthetic Communications

Year:

1993

Language:

english

File:

PDF, 257 KB

english, 1993

40

The temporal course of intracranial haemorrhage progression: How long is observation necessary?

Adena Homnick, Ziad Sifri, Peter Yonclas, Alicia Mohr, David Livingston

Journal:

Year:

2012

Language:

english

File:

PDF, 198 KB

english, 2012

41

Evaluation of genetic counseling among cystic fibrosis carriers, Michigan Newborn Screening

Kleyn, Mary J., Langbo, Carrie, Abdulhamid, Ibrahim, Adamski, Craig R., Allan, Catherine, Carmany, Erin P., Gregoire-Bottex, M. Myrtha, Homnick, Douglas, Schuen, John, Nasr, Samya Z.

Journal:

Pediatric Pulmonology

Year:

2013

Language:

english

File:

PDF, 70 KB

english, 2013

42

Modular electron donor group tuning of frontier energy levels in diarylaminofluorenone push–pull molecules

Homnick, Paul J., Lahti, Paul M.

Journal:

Physical Chemistry Chemical Physics

Year:

2012

Language:

english

File:

PDF, 2.39 MB

english, 2012

43

Asymmetric Synthesis of α,α-Difluoro-β-amino Acid Derivatives from Enantiomerically Pure N-tert- Butylsulfinimines

Staas, Donnette D., Savage, Kelly L., Homnick, Carl F., Tsou, Nancy N., Ball, Richard G.

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 91 KB

english, 2002

44

9-Hydroxyazafluorenes and Their Use in Thrombin Inhibitors

Stauffer, Kenneth J., Williams, Peter D., Selnick, Harold G., Nantermet, Philippe G., Newton, Christina L., Homnick, Carl F., Zrada, Matthew M., Lewis, S. Dale, Lucas, Bobby J., Krueger, Julie A., Pie

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 223 KB

english, 2005

45

Push–pull triarylamine additives that enhance dye sensitized solar cell performance

Kokil, Akshay, Chudomel, J. Matthew, Homnick, Paul J., Lahti, Paul M., Kumar, Jayant

Journal:

Year:

2013

Language:

english

File:

PDF, 598 KB

english, 2013

46

Engineering Frontier Energy Levels in Donor–Acceptor Fluoren-9-ylidene Malononitriles versus Fluorenones

Homnick, Paul J., Tinkham, Jonathan S., Devaughn, Raymond, Lahti, Paul M.

Journal:

Journal of Physical Chemistry A

Year:

2014

Language:

english

File:

PDF, 2.82 MB

english, 2014

47

Radical cations from diarylamino-substituted fluorenones

Homnick, Paul J., Tinkham, Jonathan S., Lahti, Paul M.

Journal:

Tetrahedron Letters

Year:

2013

Language:

english

File:

PDF, 699 KB

english, 2013

48

Improved Performances in Polymer BHJ Solar Cells Through Frontier Orbital Tuning of Small Molecule Additives in Ternary Blends

Kokil, Akshay, Poe, Ambata M., Bae, Youngju, Della Pelle, Andrea M., Homnick, Paul J., Lahti, Paul M., Kumar, Jayant, Thayumanavan, S.

Journal:

ACS Applied Materials & Interfaces

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

49

Total synthesis of nonpeptidal cholecystokinin antagonists from Aspergillus alliaceus

Bock, Mark G., DiPardo, Robert M., Pitzenberger, Steven M., Homnick, Carl F., Springer, James P., Freidinger, Roger M.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 390 KB

english, 1987

50

Benzodiazepines as Potent and Selective Bradykinin B 1 Antagonists

Wood, Michael R., Kim, June J., Han, Wei, Dorsey, Bruce D., Homnick, Carl F., DiPardo, Robert M., Kuduk, Scott D., MacNeil, Tanya, Murphy, Kathy L., Lis, Edward V., Ransom, Richard W., Stump, Gary L.,

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 45 KB

english, 2003

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